| Daniel Reyes | LA Galaxy | FW | 38 | 10 | 180 |
| Emiliano Fernandez | Charlotte FC | DF | 31 | 8 | 161 |
| Martin Castillo | Charlotte FC | DF | 30 | 9 | 138 |
| Raul Delgado | Atlanta United FC | GK | 29 | 9 | 120 |
| Ezequiel Gutierrez | Atlanta United FC | FW | 28 | 7 | 124 |
| Javier Guerrero | Colorado Rapids | DF | 27 | 10 | 147 |
| Gabriel Ponce | CF Montréal | MF | 26 | 12 | 132 |
| Nicolas Flores | Toronto FC | DF | 25 | 2 | 231 |
| Ezequiel Gonzalez | St. Louis City SC | DF | 24 | 9 | 132 |
| Bruno Diaz | Orlando City SC | FW | 23 | 9 | 96 |
| Cristian Flores | Nashville SC | GK | 22 | 20 | 208 |
| Miguel Vasquez | San Jose Earthquakes | DF | 21 | 8 | 135 |
| Oscar Salazar | Philadelphia Union | MF | 19 | 6 | 79 |
| Thiago Gonzalez | Charlotte FC | MF | 18 | 6 | 132 |
| Gonzalo Reyes | Austin FC | MF | 18 | 7 | 74 |
| Daniel Espinoza | New York Red Bulls | FW | 18 | 5 | 89 |
| Daniel Morales | Colorado Rapids | FW | 17 | 1 | 68 |
| Diego Fuentes | New England Revolution | MF | 15 | 4 | 77 |
| Ignacio Nunez | Colorado Rapids | MF | 15 | 7 | 92 |
| Franco Torres | Los Angeles Football Club | FW | 15 | 5 | 103 |
| Tomas Rojas | Colorado Rapids | GK | 15 | 3 | 79 |
| Ricardo Cardenas | San Jose Earthquakes | DF | 15 | 12 | 179 |
| Juan Delgado | Columbus Crew | MF | 14 | 0 | 60 |
| Miguel Jimenez | Atlanta United FC | MF | 12 | 0 | 50 |
| Raul Rodriguez | Atlanta United FC | MF | 12 | 1 | 108 |
| Alberto Rojas | Seattle Sounders FC | GK | 12 | 1 | 60 |
| Gabriel Fernandez | Minnesota United FC | MF | 12 | 3 | 115 |
| Leandro Acosta | Portland Timbers | MF | 12 | 1 | 93 |
| Sebastian Molina | FC Dallas | DF | 11 | 10 | 101 |
| Luis Aguilar | St. Louis City SC | FW | 11 | 5 | 78 |
| Cristian Suarez | New York City FC | DF | 11 | 3 | 44 |
| Javier Sandoval | San Diego FC | MF | 11 | 3 | 93 |
| Carlos Castillo | Vancouver Whitecaps FC | MF | 11 | 6 | 116 |
| Maximiliano Diaz | Toronto FC | DF | 11 | 6 | 72 |
| Raul Gonzalez | Inter Miami CF | DF | 11 | 2 | 150 |
| Nicolas Silva | St. Louis City SC | MF | 11 | 13 | 159 |
| Gonzalo Medina | Los Angeles Football Club | MF | 10 | 1 | 90 |
| Diego Fernandez | Inter Miami CF | MF | 10 | 11 | 160 |
| Emanuel Paredes | Columbus Crew | FW | 9 | 2 | 48 |
| Alejandro Figueroa | Atlanta United FC | MF | 8 | 3 | 35 |
| Ivan Nunez | Nashville SC | FW | 8 | 9 | 100 |
| Luis Navarro | CF Montréal | MF | 8 | 10 | 132 |
| Rafael Pereira | New England Revolution | DF | 8 | 2 | 36 |
| Manuel Garcia | Real Salt Lake | FW | 7 | 3 | 78 |
| Cesar Valencia | San Diego FC | DF | 7 | 4 | 84 |
| Pablo Vega | FC Dallas | MF | 7 | 7 | 72 |
| Alberto Fuentes | Austin FC | FW | 6 | 1 | 46 |
| Ezequiel Torres | D.C. United | DF | 6 | 2 | 26 |
| Cristian Garcia | Los Angeles Football Club | DF | 5 | 1 | 144 |
| Rafael Herrera | Minnesota United FC | FW | 5 | 0 | 30 |
| Thiago Barrera | D.C. United | MF | 5 | 13 | 137 |
| Enrique Diaz | Toronto FC | FW | 5 | 2 | 155 |
| Emanuel Silva | Columbus Crew | FW | 5 | 3 | 70 |
| Roberto Castillo | San Diego FC | MF | 4 | 1 | 36 |
| Ricardo Valencia | Orlando City SC | FW | 4 | 2 | 51 |
| Leandro Navarro | Minnesota United FC | FW | 4 | 5 | 55 |
| Nicolas Morales | FC Cincinnati | DF | 4 | 6 | 84 |
| Gustavo Vasquez | LA Galaxy | MF | 4 | 1 | 53 |
| Edgar Aguilar | San Diego FC | GK | 4 | 4 | 49 |
| Oscar Garcia | Sporting Kansas City | FW | 4 | 3 | 60 |
| Alejandro Garcia | New England Revolution | MF | 3 | 0 | 24 |
| Fernando Ponce | Inter Miami CF | FW | 3 | 3 | 41 |
| Emanuel Cardenas | Austin FC | DF | 3 | 0 | 17 |
| Leandro Flores | Real Salt Lake | GK | 3 | 5 | 57 |
| Emanuel Gonzalez | LA Galaxy | MF | 3 | 2 | 28 |
| Alberto Diaz | Minnesota United FC | MF | 3 | 3 | 60 |
| Andres Gonzalez | Atlanta United FC | MF | 2 | 0 | 38 |
| Leandro Rojas | New York City FC | DF | 2 | 0 | 11 |
| Hector Castillo | Portland Timbers | DF | 2 | 0 | 52 |
| Luciano Torres | Houston Dynamo FC | DF | 2 | 1 | 31 |
| Enrique Salazar | FC Dallas | DF | 1 | 0 | 11 |
| Oscar Cruz | San Jose Earthquakes | DF | 1 | 6 | 84 |
| Pablo Vasquez | Inter Miami CF | DF | 1 | 0 | 69 |
| Victor Barrera | Atlanta United FC | MF | 1 | 1 | 22 |
| Alejandro Hernandez | Charlotte FC | MF | 1 | 1 | 23 |
| Fernando Garcia | Seattle Sounders FC | MF | 1 | 0 | 20 |
| Roberto Cabrera | Nashville SC | MF | 0 | 2 | 25 |
| Leandro Sandoval | Atlanta United FC | MF | 0 | 4 | 72 |
| Luciano Gutierrez | FC Dallas | GK | 0 | 1 | 31 |
| Alvaro Valencia | LA Galaxy | MF | 0 | 0 | 90 |
| Sergio Valencia | Colorado Rapids | MF | 0 | 16 | 161 |