7 Senegal players across Major League Soccer.
| Player | Team | Pos | Goals | Assists | Apps |
|---|---|---|---|---|---|
| Cheick Sabaly | Vancouver Whitecaps FC | FWD | 1 | 0 | 6 |
| Jamal Thiaré | Columbus Crew | FWD | 0 | 0 | 7 |
| Dieng Mamadou | Minnesota United FC | FWD | 0 | 0 | 3 |
| Fallou Fall | St. Louis CITY SC | MID | 0 | 0 | 0 |
| Mamadou Fall | St. Louis CITY SC | DEF | 0 | 0 | 1 |
| Mamadou Billo Diop | Colorado Rapids | FWD | 0 | 0 | 1 |
| Mamadou Dieng | Minnesota United FC | FWD | 0 | 0 | 7 |