| Emanuel Sandoval | San Diego FC | FW | 36 | 12 | 198 |
| Daniel SalazarDP | Philadelphia Union | GK | 34 | 12 | 150 |
| Juan Guerrero | FC Cincinnati | FW | 31 | 11 | 180 |
| Luciano Diaz | Los Angeles Football Club | GK | 30 | 8 | 168 |
| Alvaro Silva | Toronto FC | FW | 29 | 13 | 215 |
| Fernando Torres | Colorado Rapids | MF | 26 | 8 | 112 |
| Miguel Cardenas | Houston Dynamo FC | DF | 24 | 9 | 119 |
| Alberto Jimenez | Austin FC | DF | 24 | 7 | 168 |
| Gonzalo Rios | Real Salt Lake | DF | 21 | 7 | 84 |
| Juan Delgado | Real Salt Lake | DF | 21 | 9 | 102 |
| Pablo Ortiz | Seattle Sounders FC | MF | 20 | 1 | 165 |
| Gustavo Ramirez | Minnesota United FC | MF | 19 | 10 | 100 |
| Javier Soto | Los Angeles Football Club | GK | 18 | 6 | 115 |
| Diego Palacios | Los Angeles Football Club | DF | 17 | 14 | 90 |
| Santiago Gutierrez | New England Revolution | MF | 17 | 3 | 105 |
| Cristian Herrera | Toronto FC | DF | 16 | 0 | 75 |
| Ezequiel Medina | Charlotte FC | DF | 16 | 1 | 69 |
| Ignacio Navarro | Philadelphia Union | MF | 15 | 6 | 90 |
| Nicolas Reyes | Columbus Crew | FW | 14 | 9 | 138 |
| Fernando Gutierrez | Chicago Fire FC | MF | 13 | 3 | 80 |
| Alejandro Sandoval | New England Revolution | DF | 12 | 5 | 196 |
| Jorge Fuentes | D.C. United | FW | 12 | 4 | 140 |
| Gustavo Rios | Real Salt Lake | FW | 12 | 5 | 104 |
| Tomas Fernandez | New England Revolution | DF | 12 | 7 | 90 |
| Ignacio Ramirez | Portland Timbers | MF | 12 | 3 | 54 |
| Edgar Valencia | Los Angeles Football Club | DF | 11 | 3 | 50 |
| Cesar Lopez | San Diego FC | MF | 11 | 2 | 46 |
| Juan Fernandez | Philadelphia Union | DF | 11 | 8 | 162 |
| Santiago Suarez | Seattle Sounders FC | DF | 10 | 9 | 126 |
| Santiago Nunez | Portland Timbers | MF | 9 | 18 | 216 |
| Diego Guerrero | Austin FC | FW | 9 | 2 | 44 |
| Diego Lopez | Nashville SC | MF | 9 | 2 | 55 |
| Juan Garcia | Real Salt Lake | DF | 9 | 0 | 50 |
| Gabriel Flores | Real Salt Lake | MF | 9 | 16 | 189 |
| Emiliano Valencia | Houston Dynamo FC | DF | 9 | 2 | 49 |
| Gabriel Pereira | Portland Timbers | FW | 8 | 1 | 48 |
| Thiago Fernandez | San Diego FC | MF | 8 | 12 | 136 |
| Alberto Barrera | Columbus Crew | DF | 8 | 2 | 48 |
| Jorge Vasquez | Austin FC | MF | 8 | 0 | 33 |
| Franco Castillo | Chicago Fire FC | DF | 8 | 15 | 218 |
| Cesar Fernandez | Sporting Kansas City | FW | 7 | 10 | 114 |
| Thiago Acosta | Orlando City SC | FW | 7 | 2 | 52 |
| Andres Hernandez | FC Cincinnati | DF | 6 | 5 | 94 |
| Rafael Jimenez | FC Cincinnati | DF | 6 | 2 | 30 |
| Ivan Martinez | New England Revolution | MF | 6 | 5 | 120 |
| Victor Rios | D.C. United | DF | 6 | 2 | 45 |
| Luis Reyes | Philadelphia Union | MF | 5 | 14 | 150 |
| Marco Castillo | D.C. United | MF | 5 | 5 | 147 |
| Carlos Gutierrez | New England Revolution | FW | 5 | 1 | 59 |
| Sebastian Lopez | Houston Dynamo FC | DF | 5 | 1 | 68 |
| Bruno Valencia | Colorado Rapids | MF | 5 | 0 | 25 |
| Santiago Lopez | St. Louis City SC | FW | 4 | 5 | 120 |
| Sebastian Ramirez | Toronto FC | MF | 4 | 3 | 31 |
| Alejandro Molina | LA Galaxy | DF | 4 | 2 | 34 |
| Alejandro Ramos | Houston Dynamo FC | FW | 4 | 1 | 46 |
| Matias Morales | San Jose Earthquakes | DF | 4 | 0 | 18 |
| Jorge Barrera | Inter Miami CF | FW | 4 | 8 | 94 |
| Luciano Lopez | New England Revolution | DF | 4 | 4 | 44 |
| Sergio Salazar | Orlando City SC | DF | 4 | 1 | 84 |
| Cesar Cardenas | Colorado Rapids | FW | 3 | 1 | 44 |
| Gabriel Medina | Colorado Rapids | MF | 3 | 4 | 44 |
| Bruno Ramirez | Portland Timbers | GK | 3 | 3 | 112 |
| Sebastian Morales | Atlanta United FC | FW | 2 | 1 | 28 |
| Javier Mendoza | D.C. United | DF | 2 | 1 | 35 |
| Gabriel Mendoza | Los Angeles Football Club | DF | 2 | 2 | 38 |
| Miguel Ortiz | St. Louis City SC | DF | 1 | 7 | 128 |
| Alejandro Ponce | FC Cincinnati | MF | 0 | 2 | 26 |
| Gustavo Figueroa | Portland Timbers | MF | 0 | 0 | 23 |
| Hector Aguilar | Portland Timbers | MF | 0 | 1 | 14 |
| Gabriel Molina | San Jose Earthquakes | FW | 0 | 1 | 38 |