| Josef MartinezDP | Atlanta United FC | FW | 90 | 14 | 125 |
| Leandro Molina | New York City FC | MF | 57 | 14 | 248 |
| Alejandro Castillo | St. Louis City SC | GK | 48 | 12 | 260 |
| Tomas Nunez | Houston Dynamo FC | MF | 42 | 25 | 270 |
| Sebastian Mendoza | Austin FC | FW | 40 | 15 | 169 |
| Ivan Ramos | Chicago Fire FC | MF | 40 | 7 | 170 |
| Tomas Cruz | St. Louis City SC | DF | 39 | 3 | 191 |
| Facundo Silva | Charlotte FC | MF | 36 | 18 | 224 |
| Miguel Cabrera | Portland Timbers | GK | 35 | 0 | 168 |
| Gustavo Flores | New York Red Bulls | MF | 35 | 7 | 198 |
| Alejandro Barrera | New York Red Bulls | MF | 32 | 3 | 168 |
| Edgar Gonzalez | Real Salt Lake | DF | 30 | 12 | 124 |
| Alvaro Cabrera | Los Angeles Football Club | FW | 30 | 15 | 162 |
| Javier Salazar | New England Revolution | MF | 29 | 9 | 138 |
| Martin Molina | New York Red Bulls | FW | 27 | 0 | 132 |
| Daniel Fernandez | Sporting Kansas City | MF | 26 | 7 | 112 |
| Ezequiel Sandoval | Sporting Kansas City | FW | 25 | 9 | 126 |
| Franco Rios | Chicago Fire FC | DF | 23 | 5 | 120 |
| Hector Acosta | New York City FC | FW | 23 | 8 | 114 |
| Roberto Herrera | Houston Dynamo FC | MF | 23 | 6 | 101 |
| Emiliano Valencia | Nashville SC | DF | 23 | 8 | 100 |
| Matias Paredes | Orlando City SC | FW | 22 | 7 | 116 |
| Daniel Ramos | Colorado Rapids | FW | 22 | 1 | 103 |
| Alejandro Mendoza | Inter Miami CF | FW | 22 | 9 | 192 |
| Emanuel Silva | D.C. United | DF | 19 | 0 | 90 |
| Oscar Castillo | Sporting Kansas City | GK | 19 | 2 | 85 |
| Maximiliano Aguilar | FC Cincinnati | DF | 19 | 9 | 128 |
| Victor Aguilar | Columbus Crew | MF | 18 | 9 | 97 |
| Fernando Pereira | Portland Timbers | DF | 18 | 11 | 150 |
| Gabriel Reyes | FC Dallas | DF | 16 | 7 | 135 |
| Edgar Mendoza | Portland Timbers | MF | 16 | 7 | 75 |
| Raul Aguilar | San Diego FC | DF | 16 | 7 | 76 |
| Matias Medina | FC Cincinnati | MF | 15 | 3 | 60 |
| Juan Rojas | D.C. United | DF | 14 | 9 | 119 |
| Rodrigo Aguilar | Vancouver Whitecaps FC | FW | 14 | 3 | 181 |
| Javier Torres | LA Galaxy | FW | 14 | 7 | 192 |
| Luciano Cabrera | San Diego FC | MF | 13 | 3 | 71 |
| Raul Ponce | New England Revolution | MF | 13 | 3 | 160 |
| Ricardo Ramirez | Toronto FC | DF | 11 | 3 | 46 |
| Ricardo Navarro | San Diego FC | DF | 10 | 1 | 66 |
| Sergio Pereira | FC Cincinnati | GK | 10 | 2 | 72 |
| Ricardo Martinez | Orlando City SC | MF | 10 | 1 | 46 |
| Sebastian Diaz | Philadelphia Union | FW | 10 | 9 | 99 |
| Facundo Ramos | Colorado Rapids | FW | 9 | 1 | 60 |
| Andres Flores | Philadelphia Union | FW | 8 | 1 | 48 |
| Hector Lopez | Portland Timbers | FW | 8 | 1 | 33 |
| Raul Herrera | Portland Timbers | FW | 8 | 6 | 80 |
| Franco Mendoza | Atlanta United FC | MF | 8 | 3 | 76 |
| Victor Herrera | San Jose Earthquakes | GK | 8 | 2 | 48 |
| Ricardo Figueroa | Charlotte FC | DF | 7 | 3 | 48 |
| Matias Castillo | New York Red Bulls | DF | 7 | 8 | 111 |
| Thiago Vasquez | Chicago Fire FC | DF | 6 | 2 | 31 |
| Emanuel Castillo | Colorado Rapids | DF | 6 | 2 | 80 |
| Javier Martinez | LA Galaxy | DF | 6 | 4 | 62 |
| Cesar Ponce | Los Angeles Football Club | GK | 6 | 0 | 24 |
| Raul Barrera | Philadelphia Union | DF | 6 | 1 | 88 |
| Alvaro Pereira | Columbus Crew | DF | 6 | 1 | 71 |
| Emiliano Lopez | Colorado Rapids | DF | 6 | 5 | 160 |
| Raul Vasquez | San Diego FC | MF | 6 | 1 | 24 |
| Diego Flores | Sporting Kansas City | FW | 5 | 2 | 30 |
| Fernando Flores | San Jose Earthquakes | DF | 5 | 2 | 96 |
| Gonzalo Silva | New England Revolution | DF | 5 | 3 | 36 |
| Gonzalo Cabrera | Charlotte FC | DF | 4 | 3 | 34 |
| Gabriel Fernandez | New York Red Bulls | DF | 4 | 3 | 36 |
| Luciano Ponce | Portland Timbers | DF | 4 | 0 | 153 |
| Luis Fuentes | FC Cincinnati | MF | 4 | 1 | 25 |
| Manuel Cruz | Minnesota United FC | MF | 4 | 1 | 46 |
| Marco Gonzalez | FC Dallas | FW | 3 | 1 | 17 |
| Luciano Ramirez | Sporting Kansas City | DF | 3 | 0 | 29 |
| Leandro Gutierrez | Atlanta United FC | DF | 3 | 4 | 96 |
| Emiliano Aguilar | Nashville SC | DF | 3 | 0 | 75 |
| Luciano Fuentes | Real Salt Lake | MF | 3 | 7 | 87 |
| Gustavo Diaz | D.C. United | DF | 3 | 1 | 110 |
| Pablo Cruz | Minnesota United FC | MF | 3 | 1 | 15 |
| Edgar Medina | St. Louis City SC | MF | 2 | 1 | 21 |
| Ivan Aguilar | Philadelphia Union | DF | 2 | 0 | 19 |
| Edgar Espinoza | Portland Timbers | FW | 2 | 0 | 15 |
| Carlos Aguilar | FC Dallas | DF | 2 | 2 | 42 |
| Gabriel Torres | Sporting Kansas City | MF | 1 | 1 | 17 |
| Sergio Ortiz | San Jose Earthquakes | MF | 1 | 5 | 51 |
| Ezequiel Navarro | New York City FC | MF | 1 | 7 | 78 |
| Alvaro Nunez | LA Galaxy | DF | 0 | 1 | 16 |
| Hector Sandoval | Columbus Crew | GK | 0 | 2 | 72 |
| Roberto Medina | FC Cincinnati | GK | 0 | 0 | 23 |
| Thiago Valencia | CF Montréal | DF | 0 | 0 | 20 |
| Miguel Cardenas | Sporting Kansas City | MF | 0 | 0 | 34 |