17 Venezuela players across Major League Soccer.
| Player | Team | Pos | Goals | Assists | Apps |
|---|---|---|---|---|---|
| Kevin Kelsy | Portland Timbers | FWD | 9 | 4 | 21 |
| David Martínez | LAFC | FWD | 6 | 1 | 18 |
| Wikelman Carmona | CF Montréal | MID | 4 | 4 | 13 |
| Telasco Segovia | Inter Miami CF | MID | 3 | 8 | 20 |
| Ender Echenique | FC Cincinnati | FWD | 1 | 5 | 20 |
| Jesús Bueno | Philadelphia Union | MID | 1 | 2 | 16 |
| Sergio Córdova | St. Louis CITY SC | FWD | 1 | 0 | 10 |
| Ronald Hernández | Atlanta United FC | DEF | 0 | 0 | 7 |
| Santiago Pita | Atlanta United FC | MID | 0 | 0 | 0 |
| Dani Pereira | Austin FC | MID | 0 | 0 | 7 |
| Miguel Navarro | Colorado Rapids | DEF | 0 | 1 | 16 |
| Javier Otero | Orlando City SC | GK | 0 | 0 | 2 |
| Gustavo Caraballo | Orlando City SC | FWD | 0 | 0 | 0 |
| Giovanny Sequera | Philadelphia Union | DEF | 0 | 0 | 1 |
| Carlos Zarzalejo | New England Revolution | MID | 0 | 0 | 0 |
| Josef Martínez | Columbus Crew | FWD | 0 | 0 | 4 |
| Rafael Uzcátegui | Philadelphia Union | DEF | 0 | 0 | 0 |