| 1 | Landon Donovan |  LA Galaxy | United States | 14 | 251 |
| 2 | Jaime Moreno |  D.C. United | Bolivia | 14 | 235 |
| 3 | Chris Wondolowski |  San Jose Earthquakes | United States | 17 | 212 |
| 4 | Diego Valeri |  Portland Timbers | Argentina | 10 | 177 |
| 5 | Robbie Keane | LA Galaxy | Ireland | 6 | 149 |
| 6 | Dwayne De Rosario | D.C. United | Canada | 13 | 144 |
| 7 | Sebastian Giovinco |  Toronto FC | Italy | 5 | 134 |
| 8 | Preki |  Sporting Kansas City | United States | 9 | 134 |
| 9 | Bradley Wright-Phillips |  New York Red Bulls | England | 8 | 133 |
| 10 | Taylor Twellman |  New England Revolution | United States | 8 | 123 |
| 11 | Eduard Atuesta | Los Angeles Football Club | Colombia | 11 | 119 |
| 12 | Carlos Vela | Los Angeles Football Club | Mexico | 6 | 118 |
| 13 | Ezequiel Barco |  Atlanta United FC | Argentina | 13 | 115 |
| 14 | Ricardo Clark |  Houston Dynamo FC | United States | 3 | 113 |
| 15 | Kellyn Acosta | Los Angeles Football Club | United States | 11 | 112 |
| 16 | Carlos Ruiz | LA Galaxy | Guatemala | 8 | 111 |
| 17 | Nery Castillo |  Chicago Fire FC | Mexico | 7 | 111 |
| 18 | Conor Casey |  Colorado Rapids | United States | 11 | 109 |
| 19 | David Villa |  New York City FC | Spain | 4 | 108 |
| 20 | Brenner |  FC Cincinnati | Brazil | 11 | 108 |
| 21 | Jacob Shaffelburg |  Nashville SC | Canada | 8 | 108 |
| 22 | Chris Klein | LA Galaxy | United States | 6 | 107 |
| 23 | Clint Dempsey |  Seattle Sounders FC | United States | 7 | 106 |
| 24 | Federico Higuain |  Columbus Crew | Argentina | 11 | 106 |
| 25 | Josef Martinez | Atlanta United FC | Venezuela | 5 | 104 |
| 26 | Marco Etcheverry | D.C. United | Bolivia | 8 | 104 |
| 27 | Brad Davis | Houston Dynamo FC | United States | 6 | 102 |
| 28 | Karol Swiderski |  Charlotte FC | Poland | 8 | 102 |
| 29 | Nicolas Lodeiro | Seattle Sounders FC | Uruguay | 8 | 100 |
| 30 | Graham Zusi | Sporting Kansas City | United States | 14 | 98 |
| 31 | John Harkes | D.C. United | United States | 4 | 97 |
| 32 | Javier Morales |  Real Salt Lake | Argentina | 12 | 97 |
| 33 | Joao Pedro |  Austin FC | Brazil | 13 | 97 |
| 34 | Jozy Altidore | Toronto FC | United States | 12 | 96 |
| 35 | Lee Nguyen | New England Revolution | United States | 6 | 96 |
| 36 | Alexander Ring | New York City FC | Finland | 5 | 96 |
| 37 | Teemu Pukki |  Minnesota United FC | Finland | 8 | 96 |
| 38 | Dax McCarty | New York Red Bulls | United States | 14 | 95 |
| 39 | Ethan Finlay | Minnesota United FC | United States | 4 | 94 |
| 40 | Thierry Henry | New York Red Bulls | France | 5 | 93 |
| 41 | Jesse Marsch | D.C. United | United States | 5 | 93 |
| 42 | Kenny Cooper |  FC Dallas | United States | 3 | 92 |
| 43 | Mark Anthony Kaye | Los Angeles Football Club | Canada | 9 | 91 |
| 44 | Marcus Ingvartsen |  San Diego FC | Denmark | 3 | 91 |
| 45 | Luciano Acosta | FC Cincinnati | Argentina | 6 | 90 |
| 46 | Fredy Montero | Seattle Sounders FC | Colombia | 7 | 90 |
| 47 | Robin Lod | Minnesota United FC | Finland | 5 | 90 |
| 48 | Jermaine Jones | New England Revolution | United States | 14 | 89 |
| 49 | Jordan Morris | Seattle Sounders FC | United States | 9 | 88 |
| 50 | Eric Wynalda | San Jose Earthquakes | United States | 8 | 88 |